Novel natural products from bacteria with antiviral activity against HCV

 

In a collaboration that started between two German groups but now includes an Albertan group as well, a library of secondary metabolites of soil bacteria was tested to identify compounds with activities against HCV. Several compounds that inhibit HCV replication were identified. More recently several compounds were identified to inhibit HCV infectivity. This is the first evaluation of this library for antiviral activities.

LINKS:

http://www.sciencedirect.com/science/article/pii/S0166354210008247

http://www.sciencedirect.com/science/article/pii/S0168827815003918

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